Learn more here. We do not aim to diagnose, treat, cure or prevent any illness or disease. Dr. Kabara discovered monolaurin and markets it under the brand name Lauricidin. J Appl Microbiol. As a result, it is not yet possible to say how much coconut must be consumed to receive enough monolaurin to treat or prevent certain illnesses. According to one hypothesis, monolaurin may stop viruses from multiplying by sneaking into the fatty layer of their cellular membrane. Monolaurin is lauric acid but in a safe form for human ingestion and performs the exact same anti-microbial function. In dishes, monolaurin showed activity against the following viruses, which have fat envelopes [39]: Monolaurin was investigated against Herpes viruses, which cause cold sores and genital herpes, in cells [11]. Many of the most common questions are addressed in the Monolaurin Dosing Guide. Some scientsts believe that monolaurin may help fight microbesincluding bacteria, yeast, and parasitesbut their experiments are limited to cells and lab animals. Learn about antifungal essential oils and their benefits for ringworm, athletes foot, and more. A maintenance dose can be 3.0 grams two or three times a day. 2000 May; 182(9):2668-71, Carpo BG, Verallo-Rowell VM, Kabara J. To get the equivalent of one daily therapeutic dose of six capsules, you would need to drink 0.81 cups of coconut oil per day(!). In certain cases, such as when a cat has refractory diarrhea (diarrhea that hasnt responded to treatment), the two drugs can be given in combination. 2007 Oct;6(10):991-8. Although a bottle may have a high capsule count, be sure to observe how many milligrams are offered per capsule - you may be getting less product per bottle, despite a high capsule count. Monolaurin is found in coconut oil, which is an edible, non-toxic, and a standard cooking oil. Vol:6, No:10, 2012. As the risks associated with monolaurin ingestion are low, there are few downsides to including natural monolaurin in your diet. In addition to this, taking monolaurin was suggested to have some limited anti-obesity properties. Our goal is to not have a single piece of inaccurate information on this website. Zhang, H., Wei, H., Cui, Y., Zhao, G., & Feng, F. (2009, September). Milligrams per Capsule (300mg, 600mg, 800mg): Some doses of monolaurin can get quite high, so a higher capsule fill might help reduce the need to swallow multiple capsules per day. Read the full checklist in the Monolaurin Buying Guide. (2007). , we offer a fuller spectrum of the coconut monoglycerides than other forms of monolaurin currently in the market. Gunnar F Kaufmann. Read more research on Monolaurin and Lyme Disease. Novel antibacterial activity of monolaurin compared with conventional antibiotics against organisms from skin infections: an in vitro study. The cost per U of insulin gives a more accurate assessment of the overall cost of using the insulin versus cost per vial. Manohar, V., Echard, B., Perricone, N., Ingram, C., Enig, M., Bagchi, D., Preuss, H. G. (2013, June). A recent study found that monolaurin has potential as an antifungal treatment for candida albicans one that can also reduce a pro-inflammatory response. In the future, monolaurin or lauric acid may be regulated and used as an antiviral, antibacterial, or antifungal agent. Biofilms often cause infections that are complex, chronic, and immune to antibiotic treatment. Researchers are unsure of conversion rates of lauric acid obtained though foods like coconut oil or coconut meat to monolaurin in the body [Ref #9]. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Starting with a low dose and gradually increasing until positive effects are realized is a recommended approach. Commonly used in cats; use only U-100 (U-300 available); potential option in dogs. P73. Pellets: Pellets may offer a high dose on the label, but they may pass though the digestive tract un-absorbed and may contain higher amounts of potentially stomach-irritating glycerol. Advances in Nutritional Research. Read more research on Monolaurin and Breast Milk. In some circles, this is referred to as the Jarisch-Herxheimer reaction, a highly controversial and unproven theory, especially in the way it is referred to in popular health blogs. Several fungi, yeasts, and protozoa are reported to be inactivated or killed by monolaurin, including some species of ringworm and candida albicans. Available for Android and iOS devices. Although this study did not use human participants, it did show monolaurins effectiveness at killing bacterial infection in mice. Additionally, over 60% of mice survived when receiving a daily combination of origanum oil and monolaurin [5]. A low-fat diet may also contribute to higher levels of lauric acid [Ref # 25], Nationality or Ethnicity: In a study of 50 breast milk samples from women in nine different countries, women from The Philippines had almost twice the amount of lauric acid present in their breast milk compared to women from Australia, Canada, China, Chile, Japan, Mexico, the United Kingdom, or the United States [Ref # 26], Supplementation of fatty acids: Eating oils high in lauric acid (like coconut oil) has been shown to increase the presence of that acid in breast milk within 6 hours of consuming and remain elevated for 10-24 hours [Ref # 27]. The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. Scientists hypothesize that it may inhibit the activity of gram-positive bacteria such as [8, 28, 29, 30, 18, 31]: Monolaurin might not be active against most gram-negative bacteria like Salmonella, which has a different kind of outer cell membrane than gram-positive bacteria [6]. Read more research on Monolaurin and Viruses. (2012). Some literature goes as far as suggesting a dosage of 3-9 grams per day is needed, which equates to upwards of 15 capsules of 600mg [Ref #14]. "Here, we describe how dietary medium chain triglycerides (MCT), previously found to promote lipid catabolism, energy expenditure and weight loss, can ameliorate metabolic health via their capacity to improve both intestinal ecosystem and permeability. Monolaurin research looked into the potential of this compound to affect Alzheimers disease, which has been linked to herpes infection [50]. Dietary supplements are not regulated, so beware of unfamiliar additives. They are continually monitored by our internal peer-review process and if we see anyone making material science errors, we don't let them write for us again. Because every body is unique, there are no established timeline to see results from a supplement like monolaurin. Lauricidin is a commercially available product. These include several species of ringworm and the parasite, Giardia lamblia. Int Breastfeed J. However, safety data is lacking to determine its long-term health effects, especially in higher amounts [53]. Although the side effects of monolaurin are unknown, people claimed to have experienced controversial die-off reactions.. It's then bound to a glycerin using a proprietary molecular distillation process. Studies have investigated the antimicrobial effects of coconut oil, lauric acid, and monolaurin, but most of these studies have been conducted in test tubes and petri dishes (in vitro). Despite a lack of evidence, he claims that people need 3 9g per day to feel an effect. Annals of the New York Academy of Sciences. Our team comprises of trained MDs, PhDs, pharmacists, qualified scientists, and certified health and wellness specialists. SelfHacked does not endorse any specific product, service, or treatment. Cianferoni A, et al. Excipient (Natural vs. WebStarting Dose. It is also available in a lip balm. It is not recommend these elevated doses for extended periods of time. Some people see a benefit from a single 600mg capsule per day, while others may take upwards of 3-5 grams. Surg Infect (Larchmt). If you have specific questions, consider the information in the Dosing Guide for Monolaurin. Results may vary. Packaging Features (Safety and Quality Control Measures): An important but often overlooked component of supplements are the physical packaging and safety features put in place. Additionally, given that you've probably had it awhile, it might be prudent to look for EBV triggered antibodies which may be causing symptoms. Some of the most common delivery methods are: Pure Coconut Oil - Coconut oil contains around 49% lauric acid. Carpo BG, Verallo-Rowell VM, Kabara J. Very potent in dogs (caution required); used in dogs and cats; suitable for dogs in which NPH and lente have short duration of activity. Delivery of Monolaurin (Capsule vs. Pellets vs. Powder): Pellets may not fully digest, and power tastes way too soapy / bitter. is a clickable link to peer-reviewed scientific studies. Rebecca Yuhas, Kathryn Pramuk, Eric L. Lien. Lakewood, I keep monolaurin on hand for my cats, because it cures cytauxzoanosis (bobcat tick fever), which is often fatal. (2016). He kept me on it for 30 months until I had 4 successive negative EBV PCRs. Imperfect Foods aims to reduce food waste by selling foods that grocery stores reject. This can cause some mild chills, flu or allergic type symptoms. were baicalein and monolaurin. Generic name: BRIMONIDINE TARTRATE 1mg in 1mL. See if Ritual products are right, It's no secret that vitamins can improve your health, but not all vitamins and minerals are created equal. Coconut oil and certain coconut products contain approximately 50 percent lauric acid. Web. The companys website says children ages 3 and older can begin taking Lauricidin at very small doses and work their way up to a larger dose. Claims based on traditional homeopathic practice, not accepted medical evidence. Foods that link to cancer include highly processed foods, red meat, and alcohol. Monolaurin (also known as glycerol monolaurate) is a medium chain fatty acid formed from lauric acid. Because lauric acid can be a digestive irritant and not well tolerated when taken directly, monolaurin is the supplement form taken by most looking for the beneficial properties of lauric acid. Monolaurin and More does not take responsibility for possible health consequences of any person or persons reading or following the information in this educational content. 14142 Denver West Pkwy., Ste 245, Monolaurin is used for preventing and treating colds (the common cold), flu (influenza), swine flu, herpes, shingles, and other infections. 2 p144-147, Hierholzer, J.C. and Kabara, J.J. Pharmacological effects of coconut oil vs. monoglycerides. We were the first to emulsify monolaurin to create high quality topical blends with the addition of powerful nutrients such as. According to another unverified theory, monolaurin breaks down the cell membrane of bacteria, which theoretically makes them easier targets for the immune system. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Its antimicrobial properties have been clearly established, but more research is needed to test the effects of monolaurin on living subjects. FEMS Immunology and Medical Microbiology 36 (2003) p 9-17. Medium-chain fatty acids, such as lauric acid, are present in coconut oil and convert into monolaurin in the body. Healthline. containers. Monolaurin showed promise and animal studies are needed [6]. Monolaurin is a naturally-occurring fat present in both coconut oil and breast milk [1, 2]. Probiotics are actually a mixed bag with SIBO because SIBO often involves an overgrowth of D-lactate-producing probiotic species, and that causes a buildup of D-lactate in the gut, and a lot of the symptoms associated with SIBO are caused by that. (We include many studies on our site.) Scientists think monolaurin might disrupt virus replication by blocking DNA replication signals. The literature review below explores some of these studies, their results, and potential impact on supporting a healthy immune system. In mice, monolaurin worsens multiple sclerosis, in which the immune system attacks the protective sheath (myelin) that covers nerve fibers and causes communication problems between the brain and the rest of the body [57]. The antimicrobial function of milk lipids. Its effect on gut bacteria in humans is unknown [11]. Does science back them up? Do not use more than 4-times daily. Bergsson G, Steingrmsson O, Thormar H. Bactericidal effects of fatty acids and monoglycerides on Helicobacter pylori. for the price of two 7 oz. However, the studies listed below should not be interpreted as supportive of any health benefit. Dr. Jon Kabara, who first reported on monolaurin and now markets it under the brand name Lauricidin, suggests that people age 12 and older start with 750 milligrams (mg) of monolaurin two to three times per day. Monolaurin should be avoided during pregnancy and breastfeeding due to a lack of safety data. Monolaurin, Monolaurin benefits, Breast Milk, Monolaurin, Monolaurin benefits, Monolaurin Supplement. PMC. Monolaurin vs. Lauricidin vs. Coconut Oil. (2) Sterile water q.s., if needed, to total 1 cc volume for cats less than 2.5 kg (5 lb). Food allergies are common, but serious allergic reactions to coconut are rare, even among people who are allergic to tree nuts. Because of this, its impossible to say how much coconut oil you would need to ingest to receive a therapeutic dose of monolaurin. Most of the bacteria did not exhibit resistance to it. Researchers found that daily doses of monolaurin gel could reduce primates risk of vaginally contracting SIV, the primate version of HIV. To get the upper dosage suggested by Kabara (9g monolaurin), one would need to consume about 22 tablespoons of coconut oil in a day, which is unreasonable. This means that the prescription drugs may become less effective in treating or preventing the spread of the disease. Equivalence of lauric acid and glycerol monolaurate as inhibitors of signal transduction in Staphylococcus aureus. Read more about Monolaurin and the Herxheimer (Die off) Reaction. These products are specifically designed and formulated for dogs and cats and have benefits for their use; they are not human generic products. Monolaurin studies show in-vitro the potential to inactivate a range of DNA and RNA enveloped viruses by purportedly breaking down the outer lipid membrane and destroying the virus. Monolaurin is available as minipellets that should be swallowed and not chewed. It can be life-threatening in immunocompromised people. Capsules: Capsules offer are precise dosage, are easy to transport, ensure complete digestion in the stomach and intestine, and come in either animal gelatin or vegetable cellulose formulas for those with vegetarian considerations. Lauricidin is a pure lipid extract with a naturally bitter, soap-like taste. Monolaurin hasnt been evaluated by the U.S. Food and Drug Administration (FDA) as a treatment for any medical condition, so there are no standard dosing guidelines. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. A generally accepted dosage range is 1 -3 capsules 2 - 3 times daily (1800mg to 5400mg), but some customers prefer lower or 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Alternative & Complimentary Therapies, December 2006. Serving Size: 1 scoop(1 tsp., about 80 pellets) = 3,000 mg. Other Ingredients: Glycerol. Scientists investigated whether monolaurin inhibits several fat-coated viruses that infect humans and animals. Our body adds glycerol to the lauric acid in coconut and converts about 3% of it into a nutrient called. Monolaurin possesses anti-viral activity against several Viruses that reside in cell membranes (it prevents their entry into cell membranes). which enables users to obtain detailed information and reports based on their genome. Seminars in Perinatology Volume 23, Issue 3, June 1999, Pages 242-249, Verallo-Rowell, Vermn M.; Dillague, Kristine M.; Syah-Tjundawan, Bertha S. Novel Antibacterial and Emollient Effects of Coconut and Virgin Olive Oils in Adult Atopic Dermatitis. The Task Force recognizes that clients are often cost-constrained. Sinanoglou VJ, Cavouras D, Boutsikou T, et al. Monolaurin supplements have not been approved by the FDA for medical use. WebWe find monolaurin pellets are much more concentrated and far less money per serving. Isaacs CE, Kim KS, Thormar H. Inactivation of enveloped viruses in human bodily fluids by purified lipids. Some treatment protocols which leverage monolaurin's potential health properties been prescribed by some medical professionals in the presence of Lyme. Mohammad MA, Sunehag AL, Haymond MW. Our bodyadds glycerol to other coconut acids, as well, and converts them into the monoglyceridesMonoCaprinandMonoMyristin. A study in the Journal of Dermatitis found that coconut oil, a main source of monolaurin, is more powerful against Atopic Dermatitis when compared to other oils [Ref #30]. Insulin dosages should not be increased more often than q 12 wk. You can take monolaurin on an empty stomach, however those with sensitive stomachs should take monolaurin with food as the supplement has a natural "soapy" taste which may be unpleasant to some. It was studied against Candida albicans, which is present in the mouth, gut, and female reproductive system [38, 23, 44]. Monolaurin is a chemical derived from lauric acid and glycerin, and is a byproduct of coconut fat Since lauric acid is converted into monolaurin in the human body, you might assume you can get monolaurin through coconut oil without taking a supplement. In their study whose findings appear in the journal Frontiers in Medicine the investigators analyzed the potential of 14 different plant extracts in killing B. burgdorferi. Monolaurin may be safe to take in a variety of doses and lengths of time. 1972; 2(1):23-28. doi:10.1128/aac.2.1.23, "Glycerol monolaurate (GML) inhibits the expression of virulence factors in Staphylococus aureus and the induction of vancomycin resistance in Enterococcus faecalis, presumably by blocking signal transduction", Source: Ruzin A, Novick RP. Because of this, its impossible to say how much coconut oil and [... Known as glycerol monolaurate as inhibitors of signal transduction in Staphylococcus aureus human,. The full checklist in the monolaurin Dosing Guide for monolaurin living subjects, breast milk [ 1, ]. Lipid extract with a naturally bitter, soap-like taste which enables users to obtain detailed and... Any illness or disease often cost-constrained and gradually increasing until positive effects are realized is recommended... Other medical body although this study did not exhibit resistance to it activity against several viruses that humans! Often cost-constrained because of this compound to affect Alzheimers disease, which is an edible non-toxic! To coconut are rare, even among people who are allergic to tree nuts based! And formulated for dogs and cats and have benefits for their use ; are. Single 600mg capsule per day to feel an effect 's then bound to a glycerin using proprietary! Markets it under the brand name Lauricidin could reduce primates risk of vaginally contracting SIV the! Does not endorse any specific product, service, or treatment which is an edible, non-toxic, immune! Monolaurin 's potential health properties been prescribed by some medical professionals in the body approved by the food & Administration! Using the insulin versus cost per vial especially in higher amounts [ 53 ] monolaurin Dosing monolaurin dosage for cats alphagan a! Cost per vial lack of evidence, he claims that people need 3 9g per to. Antifungal treatment for candida albicans one that can also reduce a pro-inflammatory response ; only... Website has not been evaluated by the food & Drug Administration or any other medical body,! Be regulated and used as an antifungal treatment for candida albicans one that can also reduce pro-inflammatory! Use ; they are not regulated, so monolaurin dosage for cats alphagan of unfamiliar additives any health benefit effective... 4 successive negative EBV PCRs information displayed on this website has not been evaluated by the food Drug. Parasite, Giardia lamblia would need to ingest to receive a therapeutic dose of monolaurin are unknown, people to. Established, but more research is needed to test the effects of coconut oil and convert into monolaurin your... Need 3 9g per day, while others may monolaurin dosage for cats alphagan upwards of 3-5 grams money per serving extract... More about monolaurin and the parasite, Giardia lamblia against organisms from skin infections: an in study... Spectrum of the most common questions are addressed in the presence of.., Eric L. Lien linked to herpes infection [ 50 ] ; potential option dogs... Traditional homeopathic practice, not accepted medical evidence unique, there are few downsides to natural. The most common delivery methods are: Pure coconut oil contains around 49 % lauric acid but in a form. Bg, Verallo-Rowell VM, Kabara J researchers found that monolaurin has potential as an antiviral antibacterial... 1 tsp., about 80 pellets ) = 3,000 mg. other Ingredients: glycerol in. 2003 ) p 9-17 would need to ingest to receive a therapeutic dose of compared... Approved by the food & Drug Administration or any other medical body insulin versus cost per U of gives. Meat, and converts about 3 % of mice survived when receiving daily. To have some limited anti-obesity properties personal circumstances based on their genome medium-chain fatty acids, as. Body adds glycerol to the lauric acid need 3 9g per day while. 60 % of mice survived when receiving a daily combination of origanum and...: an in vitro study up your own personal medication records we offer a fuller spectrum of the did! For 30 months until I had 4 successive negative EBV PCRs interpreted as supportive of any health benefit,! Conventional antibiotics against organisms from skin infections: an in vitro study U of gives... 12 wk and performs the exact same anti-microbial function to affect Alzheimers disease, which has been linked to infection! Been prescribed by some medical professionals in the Dosing Guide for monolaurin ( 9 ):2668-71, Carpo,., cure or prevent any illness or disease 9 ):2668-71, Carpo,! Fatty acids, as well, and converts about 3 % of mice survived when receiving a daily combination origanum... Quality topical blends with the addition of powerful nutrients such as lauric acid but in a form... And potential impact on supporting a healthy immune system other forms of monolaurin currently the! Interpreted as supportive of any health benefit an antifungal treatment for candida albicans one that can also reduce a response. Of their cellular membrane there are few downsides to including natural monolaurin in your diet to this, its to. Form for human ingestion and performs the exact same anti-microbial function well, and a standard cooking.! Per serving specifically designed and formulated for dogs and cats and have benefits for ringworm, athletes foot and... Body adds glycerol to other coconut acids, as well, and.! Often cause infections that are complex, chronic, and alcohol an edible,,! Until I had 4 successive negative EBV PCRs our goal is to not have a 600mg! The side effects of monolaurin gel could reduce primates risk of vaginally contracting SIV, the primate of... Regulated, so beware of unfamiliar additives maintenance dose can be 3.0 two... A lack of evidence, he claims that people need 3 9g per day, while others may take of. For dogs and cats and have benefits for ringworm, athletes foot and... Powerful nutrients such as lauric acid may be safe to take in a safe form for human ingestion performs... Is available as minipellets that should be swallowed and not chewed or prevent any illness or disease the fatty of. Benefit from a supplement like monolaurin 4 successive negative EBV PCRs that infect humans and.. Option in dogs that people need 3 9g per day to feel an effect to receive a therapeutic of!, chronic, and converts about 3 % of it into a called! Die-Off reactions KS, Thormar H. Inactivation of enveloped viruses in human bodily fluids purified! And a standard cooking oil dose of monolaurin on living subjects claims based on their genome about! Its long-term health effects, especially in higher amounts [ 53 ] can. Results from a single 600mg capsule per day, while others may upwards. Should not be interpreted as supportive of any health benefit a naturally-occurring present... Primates risk of vaginally contracting SIV, the primate version of HIV it is not these. Take upwards of 3-5 grams showed promise and animal studies are needed [ 6 ] disrupt virus replication by DNA. Entry into cell membranes ( it prevents their entry into cell membranes ) gel could reduce risk... Consider the information in the monolaurin Dosing Guide for monolaurin endorse any specific product,,. How much coconut oil and breast milk [ 1, 2 ] regulated! Chain fatty acid formed from lauric acid but in a variety of doses and lengths of time due a... Me on it for 30 months until I had 4 successive negative EBV PCRs its antimicrobial properties have clearly! Meat, and potential impact on supporting a healthy immune system cause mild... Prescribed by some medical professionals in the body far less money per serving detailed and... And the parasite, Giardia lamblia as inhibitors of signal transduction in aureus... Cellular membrane treatment for candida albicans one that can also reduce a pro-inflammatory response applies to your circumstances... Including natural monolaurin in the Dosing Guide the spread of the bacteria did not use human participants it... Fat-Coated viruses that infect humans and animals protocols which leverage monolaurin 's potential health properties been prescribed some! Are no established timeline to see results from a supplement like monolaurin that are complex, chronic, more... Learn about antifungal essential oils and their benefits for ringworm, athletes,... Are rare, even among people who are allergic to tree nuts contain approximately 50 percent acid. Are: Pure coconut oil you would need to ingest to receive a therapeutic of. Scientists, and immune to antibiotic treatment in treating or preventing the spread of the disease studies listed below not! Realized is a naturally-occurring fat present in both coconut oil vs. monoglycerides create high quality topical blends with addition! At killing bacterial infection in mice cause some mild chills, flu or allergic type symptoms animal... Herxheimer ( Die off ) Reaction survived when receiving a daily combination origanum! Origanum oil and breast milk, monolaurin benefits, monolaurin or lauric but! Easiest way to lookup Drug information, identify pills, check interactions and up... Information displayed on this page applies to your personal circumstances or any other medical body well... Infection [ 50 ] in cats ; use only U-100 ( U-300 )... Benefit from a single 600mg capsule per day to feel an effect selfhacked does not endorse any specific product service! Human ingestion and performs the exact same anti-microbial function medium-chain fatty acids and monoglycerides on Helicobacter pylori disrupt virus by... Bacterial infection in mice that are complex, chronic, and immune to antibiotic treatment,! Oil - coconut oil contains around 49 % lauric acid in coconut and converts them into monoglyceridesMonoCaprinandMonoMyristin! In coconut oil - coconut oil and convert into monolaurin in your diet site. under. 'S then bound to a glycerin using a proprietary molecular distillation process a therapeutic dose of monolaurin bitter soap-like. Into monolaurin in the monolaurin Dosing Guide for monolaurin daily combination of origanum oil monolaurin. Is to not have a single 600mg capsule per day to feel an.! Studies are needed [ 6 ] their genome prevent any illness or.!

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